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现在位置首页>技术资料首页>行业动态>公司动态>Life Technologies和SG Biofuels共同完成了桐油树(麻风树)基因组的测序

Life Technologies和SG Biofuels共同完成了桐油树(麻风树)基因组的测序

Life Technologies2010年10月27日 16:40 点击:2901

美国Life Technologies 

 

Life Technologies公司-一家生命科学创新解决方案的供应商和SG Biofuels公司-一家生物能源作物公司,近日宣布他们已经利用Life Technologies的SOLiD™ 4.0系统,完成了桐油树(Jatropha curcas,又称麻风树)基因组的测序,覆盖度达100倍。序列大大加速了油籽生产作物关键性状的鉴定,并促进了它作为高产量、低成本的新一代生物燃料来源的开发。

通过与Life Technologies的战略同盟合作,SG Biofuels将使用这些序列产生一个高质量的桐油树参考基因组。此基因组将与SG Biofuels种质库中产生的序列进行比较,以鉴定出分子标志物和性状基因,以便加速产量和收益率极佳的优良品种的开发。SG Biofuels的种质库包含6,000多个特有的桐油树基因型,是世界上最大最多样化的桐油树种质集合。

 

 

桐油树是一种不可食用的灌木,原产于中美洲。它的种子含有大量的油,可作为多种生物型材料,包括柴油、石油化工和航空燃料工业的原料替代品。它可在粮食作物不理想的边缘地带高效生长,使它成为生物新能源的可行选择。

“与SG Biofuels合作对桐油树基因组测序,是我们广泛的合成生物学战略中的重要部分,它为新一代可再生能源的开发提供了技术,”Life Technologies合成生物学的主管Wendy Jozsi如是说。“在植物型生物能源的优化上使用先进的分子技术是一个重大机会,特别是桐油树,能使产量增加,开发周期更快,最终形成新能源。”

除了广泛的表型多样性,初步的分子标志物研究表明,SG Biofuels桐油树种质集合表现出的遗传多样性大约是印度、非洲和亚洲桐油树集合(Basha等,2009)所观察到的10倍。

“通过拥有一个多样的植物材料集合可供比较,桐油树参考基因组的价值显著增强了,”SG Biofuels的总裁及首席执行官Kirk Haney说道。“序列为我们的开发平台增添了一种强大的新工具,让我们快速了解桐油树作为最有利可图且可持续的生物能源原料的真正潜力。”

SG Biofuels完整的育种和生物技术方法形成了JMax桐油树优化平台的基础,让研究机构、种植者和农场开发者使用该公司的种质库、参考基因组、分子标志物以及高级的生物技术和合成生物学工具,以便为世界各地不同的种植环境优化桐油树的优良品种。

关于SG Biofuels
SG Biofuels是一家生物能源作物公司,它利用育种和生物技术开发和生产桐油树的优良品种。有了最大最多样化的桐油树遗传物质库,SG Biofuels正通过一支世界一流的领导队伍,前沿的科学和遗传学,以及在农学和种植管理上的专业知识,将桐油树的机会转变成现实。SG Biofuels被《生物燃料文摘》(Biofuels Digest)评为全球五十强生物能源公司之一,被Always On评为全球百强新兴清洁技术公司之一。

Life Technologies and SG Biofuels Complete Sequence of Jatropha Genome

Sequence Combined with Largest Germplasm Library Accelerates Development of Promising Energy Crop

CARLSBAD, Calif., Aug 24, 2010 /PRNewswire via COMTEX/ --

Life Technologies Corporation (Nasdaq: LIFE), a provider of innovative life science solutions and SG Biofuels, Inc., a bioenergy crop company, today announced they have completed sequencing the Jatropha curcas genome to 100x coverage, using the SOLiD(TM) 4.0 System by Life Technologies. The sequence significantly accelerates the identification of key traits for the oilseed-producing crop and advances its development as a high yielding, low-cost source for next generation biofuel.

 

Working in strategic alliance with Life Technologies, SG Biofuels will use the sequence to generate a high quality Jatropha reference genome. The genome will be compared to sequences generated from SG Biofuels' germplasm library of more than 6,000 unique Jatropha genotypes - the largest and most diverse collection of Jatropha germplasm in the world - to identify molecular markers and trait genes to accelerate development of elite cultivars with vastly superior yields and profitability. This work will also advance the introduction of transgenic plants with further improved traits.

Jatropha curcas is a non-edible shrub that is native to Central America. Its seeds contain high amounts of oil that can be used for a variety of bio-based materials including feedstock substitutes for the diesel, petrochemical and jet fuel industries. It can be effectively grown on marginal lands that are considered undesirable for food crops, making it a viable option as a new biofuel.

"Working with SG Biofuels to sequence the Jatropha genome is an important part of our broader synthetic biology strategy to provide technologies for the development of next generation renewable energy," said Wendy Jozsi, Director of Synthetic Biology at Life Technologies. "There is significant opportunity to use advanced molecular techniques in the optimization of plant-based biofuels, especially Jatropha, for increased yields and a faster development cycle, ultimately leading to new sources of energy."

In addition to extensive phenotypic diversity, preliminary molecular marker studies illustrate that SG Biofuels Jatropha germplasm collection exhibits approximately 10 times the genetic diversity observed in a collection of Jatropha from India, Africa, and Asia (Basha et al 2009).

"The value of a Jatropha reference genome is enhanced significantly by having a diverse collection of plant material for comparison," said Kirk Haney, President and Chief Executive Officer of SG Biofuels. "The sequence adds a powerful new tool to our development platform, allowing us to rapidly unlock the true potential of Jatropha as the most profitable and sustainable biofuel feedstock."

SG Biofuels' integrated breeding and biotechnology approach forms the foundation for its JMax Jatropha Optimization Platform, providing research agencies, growers and plantation developers with access to the company's germplasm library, the reference genome, molecular markers and advanced biotech and synthetic biology tools to optimize elite Jatropha cultivars for unique growing conditions around the world.

About SG Biofuels

SG Biofuels is a bioenergy crop company using breeding and biotechnology to develop and produce elite seeds of Jatropha. With the largest and most diverse library of Jatropha genetic material, SG Biofuels is turning the opportunities of Jatropha into reality through a world-class leadership team, leading-edge science and genetics and expertise in agronomy and plantation management. SG Biofuels has been named one of the Top 50 Companies in Bioenergy by Biofuels Digest and one of the Top 100 Emerging Cleantech Companies by Always On. For more information visit http://www.sgbiofuels.com/.

About Life Technologies

Life Technologies Corporation (NASDAQ: LIFE) is a global biotechnology tools company dedicated to improving the human condition. The company's systems, consumables and services enable researchers to accelerate scientific exploration, driving to discoveries and developments that make life even better. Life Technologies customers do their work across the biological spectrum, working to advance personalized medicine, regenerative science, molecular diagnostics, agricultural and environmental research, and 21st century forensics. Life Technologies had sales of $3.3 billion in 2009, employs approximately 9,000 people, has a presence in approximately 160 countries, and possesses a rapidly growing intellectual property estate of approximately 3,900 patents and exclusive licenses. Life Technologies was created by the combination of Invitrogen Corporation and Applied Biosystems Inc., and manufactures both in-vitro diagnostic products and research use only-labeled products. For more information on how we are making a difference, please visit us online at http://www.lifetechnologies.com. Follow Life Technologies on Twitter @LIFECorporation and on Facebook. and on Facebook.

Life Technologies Safe Harbor Statement

This press release includes forward-looking statements about Life Technologies' anticipated results that involve risks and uncertainties. Some of the information contained in this press release, including, but not limited to, statements as to industry trends and Life Technologies' plans, objectives, expectations and strategy for its business, contains forward-looking statements that are subject to risks and uncertainties that could cause actual results or events to differ materially from those expressed or implied by such forward-looking statements. Any statements that are not statements of historical fact are forward-looking statements. When used, the words "believe," "plan," "intend," "anticipate," "target," "estimate," "expect" and the like, and/or future tense or conditional constructions ("will," "may," "could," "should," etc.), or similar expressions, identify certain of these forward-looking statements. Important factors which could cause actual results to differ materially from those in the forward-looking statements are detailed in filings made by Life Technologies with the Securities and Exchange Commission. Life Technologies undertakes no obligation to update or revise any such forward-looking statements to reflect subsequent events or circumstances.

SOURCE SG Biofuels, Inc.; Life Technologies Corporation

(来源: Life Technologies )


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