RECEPTORS UCG006

重组体

人糖蛋白Iba

未硫化形式

N端结构域，去糖基化突变体

CAT编号UCG006

批号A0028

产品规格表：PS-G006

40微克

产品描述

糖蛋白Iba是血小板受体糖蛋白Ib-XI-V复合物的一部分。糖蛋白

Ib-XI-V复合物介导血小板与血管损伤部位的结合。该产品包括

糖蛋白Iba的第17-306位残基，包含Von Willebrand因子的结合位点，

凝血酶和botrocetin。两个N联糖基化位点Asn37和Asn175已被

通过突变为谷氨酰胺去除。

参考序列：

备用名称：

基因编号：

NM_000173

NP_000164

瑞士宝P07359

CD42b-a

糖蛋白

2811

克隆了人GpIba的17-306位残基，该蛋白在HEK293EBNA1中过表达

细胞并纯化至同质（图1）。在天然蛋白质中，酪氨酸残基位于

将292、294和295位硫酸化。在该产物中，三种酪氨酸均未被硫酸化。

重组人GpIba（残基17-306）的计算分子量为33.5 kDa，

它包含一个C端六组氨酸标签。每个小瓶包含40 μg 0.04 mg / ml的GpIba。

储存稳定性

GpIba应储存在-80℃（至少1稳定

年）。缓冲液中含有不含防腐剂的PBS。

解冻后应存放在适当的小包装中

在-20?C或-80?C的等分试样（至少2稳定）

个月）。

产品使用限制，保修，免责声明

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产品随附说明规格和其他技术信息的文档。 U-Protein Express BV产品保证符合或

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其他损害，无论是直接的，附带的，可预见的，结果性的还是特殊的损害（包括但不限于使用损失，收益或利润），无论是

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产品符合规定的规格。

版本11/2018

Recombinant

human glycoprotein Iba

Unsulfated form

N-terminal domain, deglycosylation mutant

CAT No. UCG006

LOT No. A0028

product specification sheet: PS-G006

40 ug

Product description

Glycoprotein Iba is part of the platelet receptor Glycoprotein Ib-XI-V complex. The Glycoprotein

Ib-XI-V complex mediates binding of platelets to sites of vascular damage. This product consists

of residues 17-306 of glycoprotein Iba and contains the binding sites for Von Willebrand Factor,

thrombin and botrocetin. The two N-linked glycoslation sites , Asn37 and Asn175, have been

removed by mutation to glutamine.

Reference sequences:

Alternative names:

Gene ID:

NM_000173

NP_000164

Swiss-prot P07359

CD42b-a

GpIb-a

2811

Residues 17-306 of human GpIba were cloned, the protein was over-expressed in HEK293EBNA1

cells and was purified to homogeneity (figure 1). In the native protein the tyrosine residues at

positions 292, 294 and 295 are sulfated. In this product none of the three tyrosines are sulfated.

The calculated molecular weight of recombinant human GpIba, residues 17-306, is 33.5 kDa and

it contains an C-terminal hexahistidine tag. Each vial contains 40 μg GpIba at 0.04 mg/ml.

Storage and stability

GpIba should be stored at - 80 ?C (stable for at least 1

year). The bu°er contains PBS without preservative.

After thawing it should be stored in appropriate small

aliquots at - 20 ?C or - 80 ?C (stable for at least 2

months).

PRODUCT USE LIMITATIONS, WARRANTY, DISCLAIMER

U-Protein Express BV products contain chemicals which may be harmful if misused. Due care should be exercised with all U-Protein Express BV products to

prevent direct human contact. All products are intended For Research Use Only and ARE NOT ALLOWED FOR USE IN HUMANS. Each U-Protein Express BV

product is shipped with documentation stating speci?cations and other technical information. U-Protein Express BV products are warranted to meet or

exceed the stated speci?cations. U-Protein Express BV's sole obligation and the customer's sole remedy is limited to replacement of products free of

charge in the event products fail to perform as warranted. U-Protein Express BV makes no other warranty of any kind whatsoever, and SPECIFICALLY

DISCLAIMS AND EXCLUDES ALL OTHER WARRANTIES OF ANY KIND OR NATURE WHATSOEVER, DIRECTLY OR INDIRECTLY, EXPRESS OR IMPLIED, INCLUDING, WITHOUT LIMITATION, AS TO THE SUITABILITY, PRODUCTIVITY, DURABILITY, FITNESS FOR A PARTICULAR PURPOSE OR USE, MERCHANTABILITY,

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Version 11/2018