神经元示踪染料MM 1-43 CAS：149838-22-2

产品简介：

      MM 1-43是膜标记物1-43的缩写形式，化学名为：N-(3-triethylammoniumpropyl)-4-(4-(dibutylamino)styryl)二溴吡啶。该膜标记物也被叫做FM 1-43（FM是Molecular Probes的商标）。它是一种水溶性膜探针，属于苯乙烯染料家族。因为它的细胞毒性很小，被广泛地用于细胞生物学和神经生物学。MM 1-43在水中实质上是非荧光性的，但是在与膜结合的条件下，具有强烈荧光。它可以被标准的荧光素光学滤光器高效地激发，显现出强烈的荧光信号，当与质膜结合时。MM 1-43经常用来定量分析神经元中的胞外分泌物。用MM 1-43和相关的苯乙烯染料进行荧光成像，为洞察制备的培养物中突触前的功能提供了不可估量的价值。.

英文注释：

MM 1-43 is the abbreviation of our Membrane Marker 1-43, chemically called N-(3-triethylammoniumpropyl)-4-(4-(dibutylamino)styryl)pyridinium dibromide. MM 1-43 is chemically the same molecule of FM 1-43. In literature this membrane marker is also called FM 1-43 (FM is the trademark of Molecular Probes). It is a water-soluble membrane probe that belongs to the styryl dye family. It is widely used in cell biology and neurobiology since it has minimal toxicity to cells. MM 1-43 is virtually non-fluorescent in aqueous medium and strongly fluorescent upon binding to membrane. It is efficiently excited with standard fluorescein optical filters, and exhibits an intense fluorescent signal when associated with the plasma membrane. MM 1-43 has frequently been used to quantify exocytosis in neurons. Fluorescence imaging using MM 1-43 and related styryl dyes has provided invaluable insights into presynaptic function of synapses in culture preparations.

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