现在位置：首页>实验室原料试剂耗材>干细胞>干细胞试剂盒>bpsbioscience，79590，Cathepsin B Inhibitor Screening Assay Kit

bpsbioscience，79590，Cathepsin B Inhibitor Screening Assay Kit

产品报价：询价

更新时间：2019/2/19 16:30:44

产地：美国

品牌：bpsbioscience

型号：79590

厂商性质：生产型,贸易型,服务型,

公司名称：世联博研（北京）科技有限公司

产品关键词：筛选检测试剂盒 Assay Kit 抑制剂筛选检测试剂盒 Inhibitor Screening Assay Kit

802

访问人数

累计评论

在线询价进入展商展台

程园 : (18611717737) (010-57129142)

（联系我时，请说明是在来宝网上看到的，谢谢！）

详细信息 在线询价 资料下载

Background:

Cathepsin B is a cysteine protease that primarily functions as an endopeptidase within endolysosomal compartments in normal cells. High levels of cathepsin B are found in a wide variety of human cancers and in experimental models, such as transgenic models of murine pancreatic and mammary carcinomas, causal roles for this protein have been demonstrated in initiation, growth/tumor cell proliferation, angiogenesis, invasion, and metastasis.

Description:

The Cathepsin B Inhibitor Screening Assay Kit is designed to measure the protease activity of Cathepsin B for screening and profiling applications. The Cathepsin B assay kit comes in a convenient 96-well format, with purified Cathepsin B, its fluorogenic substrate, and Cathepsin buffer for 100 enzyme reactions. In addition, the kit includes the cathepsin inhibitor E64 for use as a control inhibitor.

Materials Required But Not Provided:

? 0.5 M DTT in aqueous solution
? Adjustable micropipettor and sterile tips
? Fluorescent microplate reader

Synonym(s):

Cathepsin B, CTSV, Amyloid Precursor Protein Secretase, CTSB, APP Secretase, activity assay kit

Supplied As:

The Cathepsin B assay kit comes in a convenient 96-well format, with purified Cathepsin B, its fluorogenic substrate, and Cathepsin buffer for 100 enzyme reactions.

Format:

COMPONENT:

Instructions for use:

See assay kit data sheet for detailed protocol.

Storage / Stability:

Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.

Application(s):

Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.

Reference(s):

1. Aggarwal, N., & Sloane, B. F. (2014). Cathepsin B: multiple roles in cancer. PROTEOMICS– Clinical Applications 8(5-6), 427-437

2. Siklos, M., BenAissa, M., & Thatcher, G. R. (2015). Cysteine proteases as therapeutic targets: does selectivity matter? A systematic review of calpain and cathepsin inhibitors. Acta Pharmaceutica Sinica B, 5(6), 506-519

Warning(s):

Avoid freeze/thaw cycles.

Scientific Category:

Protease

Product Type:

Assay Kit

世联博研（北京）科技有限公司

| 第13年

手机：18611717737

联系人：程园

电话：010-57129142

传真：010-57129142

QQ：631767688

（联系我时，请说明是在来宝网上看到的，谢谢！）

* 我要求购：
* 我的姓名：
* 我的单位：
* 我的电话：
* 我的邮箱：
我的地址：
* 信息有效期：	10天 20天一个月三个月半年信息展示过期后将自动下线，如还需采购可重新发布信息
具体要求：
* 验证码：	看不清？

bpsbioscience，79590，Cathepsin B Inhibitor Screening Assay Kit

详细信息 在线询价 资料下载

世联博研（北京）科技有限公司

相关产品分类

详细信息在线询价资料下载