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excellness弹性细胞培养板,excellness弹性细胞培养皿
excellness弹性细胞培养板,excellness弹性细胞培养皿
  • excellness弹性细胞培养板,excellness弹性细胞培养皿

excellness弹性细胞培养板,excellness弹性细胞培养皿

产品报价:询价

更新时间:2019/2/15 13:57:39

地:荷兰

牌:excellness

号:excellness

厂商性质: 生产型,贸易型,服务型,

公司名称: 世联博研(北京)科技有限公司

产品关键词: 仿生细胞培养底物   仿生细胞培养环境   excellness   弹性细胞培养皿   弹性细胞培养板  

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PrimeCoat series

The ExCellness PrimeCoat series is designed specifically to provide a biomimetic cell culture environment that improves cell characteristics and phenotype in laboratory applications.
Picture
Key features
  • PrimeCoat elastic substrates are easy to use for cell culture and subsequent analysis.

  • PrimeCoat elastic substrates are available with 6 degrees of softness within the elasticity range of body tissues: 2, 5, 10, 15, 30 and 100 kPa.

  • PrimeCoat elastic substrates are available in 4 standard formats: 100 mm diameter dishes, 40 mm diameter dishes, 24-well plates and 20x20 mm cover slips.

  • PrimeCoat elastic substrates require to be coated by the end user to promote cell adhesion.

  • PrimeCoat elastic substrates are transparent. Cells can be visualized with standard transmission light microscopes (e.g., Phase contrast, DIC).

  • PrimeCoat elastic substrates are compatible with most standard molecular or cellular techniques: immunofluorescence, immunohistochemistry, protein analysis (e.g., Western blotting, and RNA/DNA extraction).


Biomimetic cell culture substrates at reach

PrimeCoat series combines simplicity and accessibility:
  • simplicity of cell handling

  • straightforward compatibility with cell analysis tools

  • accessible prices

ExCellness in selected peer reviewed publications

In the following peer-reviewed publications, ExCellness biomimetic cell culture devices have been used or cited:
  • A. Elbediwy et al.  Enigma protein regulate YAP mechanotransduction. J Cell Sci 2018 131: jcs221788

  • F. Klingberg et al. The fibronectin ED-A domain enhances recruitment of latent TGF-β-binding protein-1 to the fibroblast matrix. J Cell Sci 2018 131: jcs201293

  • B. Liu et al. Increased substrate stiffness elicits a myofibroblastic phenotype in human lamina cribrosa cells. Investigative Ophthalmology & Visual Science February 2018, Vol.59, 803-814. doi:10.1167/iovs.17-22400

  • J. Weldrick et al. A rapid and efficient method for the isolation of postnatal murine cardiac myocyte and fibroblast cells. Revue canadienne de physiologie et pharmacologie, 2018, 96(5): 535-539

  • N Elkhatib et al. Tubular clathrin/AP-2 lattices pinch collagen fibers to support 3D cell migration. Science16 Jun 2017: Vol. 356, Issue 6343, eaal4713

  • Y Attieh et al. Cancer-associated fibroblasts lead tumor invasion through integrin-β3–dependent fibronectin assembly. J Cell Biol. 2017 Nov 6; 216(11): 3509–3520.

  • A Glentis et al. Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane. Nat Commun. 2017 Oct 13;8(1):924.

  • N Vedrenne et al. Isolation of astrocytes displaying myofibroblast properties and present in multiple sclerosis lesions. Neurochem. Res. 2017 Apr 22. 

  • X L Chen et al. MicroRNA-21 preserves the fibrotic mechanical memory of mesenchymal stem cells. Nature Materials 16, 379–389 (2017).

  • MR Zeglinski et al. Chronic expression of Ski induces apoptosis and represses autophagy in cardiac myofibroblasts. Biochim.  Biophys. Acta. 2016 Jun;1863(6 Pt A):1261-8.

  • H Chen et al. Mechanosensing by the α6-integrin confers an invasive fibroblast phenotype and mediates lung fibrosis. Nat. Commun. 2016 Aug 18;7: 12564.

  • NP Talele et al. Expression of α-Smooth Muscle Actin Determines the Fate of Mesenchymal Stromal Cells. Stem Cell Reports. 2015 Jun 9;4(6) : 1016-30.

  • V Sarrazy et al. Integrins avb5 and avb3 promote latent TGF-beta 1 activation by human cardiac fibroblast contraction. Cardiovasc Res (2014) 102 (3)

  • VF Achterberg et al. The nano-scale mechanical properties of the extracellular matrix regulate dermal fibroblast function.J Invest Dermatol. 2014 Jul;134(7):1862-72.

  • JA Cadby et al. Differences between the Cell Populations from the Peritenon and the Tendon Core with Regard to Their Potential Implication in Tendon Repair. 2014. PLoS ONE 9(3): e92474.

  • T. Grand et al. Aggravation of Cardiac Myofibroblast Arrhythmogeneicity by Mechanical Stress. Cardiovasc Res2014 Dec 1;104(3):489-500.

  • JA Cadby. Can we improve tendon healing in the horse? A multi-angle study of a multi-facet problem. ISBN: 978-90-5335-715-6.

  • A Vashist et al. Recent advances in hydrogel based drug delivery systems for the human body. J. Mater. Chem. B, 2014,2, 147-166.

  • EP van der Veer et al. The RNA-Binding Protein Quaking is a Critical Regulator of Vascular Smooth Muscle Cell Phenotype. Circ Res. 2013 Oct 12;113(9):1065-75.

  • A De Boeck et al. Differential secretome analysis of cancer-associated fibrobroblasts and bone marrow-derived precursors toidentify microenvironmental regulators of colon cancerprogression. Proteomics 2013,13,379-388.

  • C Godbout et al. The Mechanical Environment Modulates Intracellular Calcium Oscillation Activities of Myofibroblasts. PLoS One. 2013; 8(5): e64560.

  • S Constant et al. Colon Cancer: Current Treatments and Preclinical Models for the Discovery and Development of New Therapies. Drug discovery; Editor Hany A. El-Shemy. ISBN 978-953-51-0906-8.

  • JL Balestrini et al. The mechanical memory of lung myofibroblasts. Integr. Biol. 2012,4, 410-421.

  • Stem Cells and Cancer Stem Cells, Volume 8. Therapeutic Applications in Disease and Injury. Editors M.A. Hayat. ISBN 978-94-007-4797-5.

  • A Skardal et al. Bioprinted amniotic fluid-derived stem cells accelerate healing of large skin wounds. Stem Cells Transl Med. 2012 Nov;1(11):792-802. doi: 10.5966/sctm.2012-0088. Epub 2012 Oct 29.

  • A Skardal et al. Substrate elasticity controls cell proliferation, surface marker expression and motile phenotype in amniotic fluid-derived stem cells. J Mech Behav Biomed Mater. 2013 January; 17: 307-316.

  • BJ Crider et al. Myocardin-Related Transcription Factors A and B Are Key Regulators of TGF-b1-Induced Fibroblast to Myofibroblast Differentiation. Journal of Investigative Dermatology (2011) 131, 2378-2385.

  • L Follonier Castella et al. A new lock-step mechanism of matrix remodelling based on subcellular contractile events. Journal of Cell Science 123, 1751-1760.

订货信息:

 

Dishes
Product Code     Description     
01. 100.002.00     2 kPa culture surface 100 mm ?     
01. 100.005.00     5 kPa culture surface 100 mm ?     
01. 100.010.00     10 kPa culture surface 100 mm ?     
01. 100.015.00     15 kPa culture surface 100 mm ?     
01. 100.030.00     30 kPa culture surface 100 mm ?     
01. 100.100.00     100 kPa culture surface 100 mm ?     

Product Code     Description     
01. 035.002.00     2 kPa culture surface 35 mm ?     
01. 035.005.00     5 kPa culture surface 35 mm ?     
01. 035.010.00     10 kPa culture surface 35 mm ?     
01. 035.015.00     15 kPa culture surface 35 mm ?     
01. 035.030.00     30 kPa culture surface 35 mm ?     
01. 035.100.00            100 kPa culture surface 35 mm ? 
 
Multi-well plates 

Product Code     Description     
04.024.002.00     2 kPa culture surface 24-well plate     
04.024.005.00     5 kPa culture surface 24-well plate     
04.024.010.00     10 kPa culture surface 24-well plate     
04.024.015.00     15 kPa culture surface 24-well plate     
04.024.030.00     30 kPa culture surface 24-well plate     
04.024.100.00     100 kPa culture surface 24-well plate 

 

    
Cover slips

Product Code     Description 

03.020.002.00     2 kPa culture surface 20x20 mm c.slip 
03.020.005.00     5 kPa culture surface 20x20 mm c.slip 
03.020.010.00     10 kPa culture surface 20x20 mm c.slip 
03.020.015.00     15 kPa culture surface 20x20 mm c.slip 
03.020.030.00     30 kPa culture surface 20x20 mm c.slip 


世联博研(北京)科技有限公司

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