Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD.
Authors: Gupta, Urvi and Ghosh, Sayan and Wallace, Callen T and Shang, Peng and Xin, Ying and Nair, Archana Padmanabhan and Yazdankhah, Meysam and Strizhakova, Anastasia and Ross, Mark A and Liu, Haitao and Hose, Stacey and Stepicheva, Nadezda A and Chowdhury, Olivia and Nemani, Mihir and Maddipatla, Vishnu and Grebe, Rhonda and Das, Manjula and Lathrop, Kira L and Sahel, José-Alain and Zigler, J Samuel and Qian, Jiang and Ghosh, Arkasubhra and Sergeev, Yuri and Handa, James T and St Croix, Claudette M and Sinha, Debasish
Journal: Autophagy (2023): 92-111
Naringenin is a Potential Immunomodulator for Inhibiting Liver Fibrosis by Inhibiting the cGAS-STING Pathway.
Authors: Chen, Li and Xia, Siwei and Wang, Shuqi and Zhou, Yuanyuan and Wang, Feixia and Li, Zhanghao and Li, Yang and Kong, Desong and Zhang, Zili and Shao, Jiangjuan and Xu, Xuefen and Zhang, Feng and Zheng, Shizhong
Journal: Journal of clinical and translational hepatology (2023): 26-37
Chemical Synthesis of the Fluorescent, Cyclic Dinucleotides cth GAMP.
Authors: Veth, Simon and Fuchs, Adrian and ?zdemir, Dilara and Dialer, Clemens and Drexler, David Jan and Knechtel, Fabian and Witte, Gregor and Hopfner, Karl-Peter and Carell, Thomas and Ploetz, Evelyn
Journal: Chembiochem : a European journal of chemical biology (2022): e202200005
Therapeutic targeting of STING-TBK1-IRF3 signalling ameliorates chronic stress induced depression-like behaviours by modulating neuroinflammation and microglia phagocytosis.
Authors: Duan, Na and Zhang, Yanpeng and Tan, Shuwen and Sun, Jianyu and Ye, Mao and Gao, Hui and Pu, Kairui and Wu, Meiyan and Wang, Qiang and Zhai, Qian
Journal: Neurobiology of disease (2022): 105739
Mechanisms of phase-separation-mediated cGAS activation revealed by dcFCCS.
Authors: Yao, Yirong and Wang, Wenjuan and Chen, Chunlai
Journal: PNAS nexus (2022): pgac109
Development of a High-Throughput Assay to Identify Inhibitors of ENPP1.
Authors: Kumar, Meera and Lowery, Robert G
Journal: SLAS discovery : advancing life sciences R & D (2021): 740-746
Connexin and gap junctions: perspectives from biology to nanotechnology based therapeutics.
Authors: Jindal, Shlok and Chockalingam, S and Ghosh, Siddhartha Sankar and Packirisamy, Gopinath
Journal: Translational research : the journal of laboratory and clinical medicine (2021): 144-167
Dysfunctional telomeres trigger cellular senescence mediated by cyclic GMP-AMP synthase.
Authors: Abdisalaam, Salim and Bhattacharya, Souparno and Mukherjee, Shibani and Sinha, Debapriya and Srinivasan, Kalayarasan and Zhu, Mingrui and Akbay, Esra A and Sadek, Hesham A and Shay, Jerry W and Asaithamby, Aroumougame
Journal: The Journal of biological chemistry (2020): 11144-11160
Development of novel highly sensitive methods to detect endogenous cGAMP in cells and tissue.
Authors: Miyakawa, Shuuichi and Okui, Toshitake and Shiraishi, Tsubasa and Yoshihara, Tomoki and Hirayama, Megumi and Satomi, Yoshinori and Hamada, Teruki and Nishida, Mayumi and Akimoto, Chihiro and Sato, Shuji
Journal: Journal of immunological methods (2020): 112751
[Effect of cyclic GMP-AMP synthase on EMT in breast cancer cells].
Authors: Zhang, Xiao-Jin and Zhang, Wen-Xia and Zhu, Ji-Ling and Luo, Wen-Pan
Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology (2020): 336-339
