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现在位置首页>实验室原料试剂耗材>化学试剂>材料科学>MQR2.4401 anti-IL8
MQR2.4401	anti-IL8
MQR2.4401	anti-IL8
  • MQR2.4401	anti-IL8

MQR2.4401 anti-IL8

产品报价:询价

更新时间:2023/4/3 18:11:18

地:美国

牌:ImmunoPrecise

号:MQR2.4401

厂商性质: 生产型,

公司名称: 世联博研(北京)科技有限公司

产品关键词: human anti-Interleukin 8 antib   human anti-Interleukin 8   anti-IL8   MQR2.4401   MQR2.4401 anti-IL8  

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品名


单克隆人抗IL8免疫球蛋白


货号。


MQR 2.4401号


批号。


18313年


数量


100微克


版本:2019年9月11日


预期用途


本产品仅供研究使用。不用于诊断或


治疗程序。


该产品经测试可用于酶联免疫吸附试验


(ELISA)。


提供试剂


抗体以PBS形式提供。


同型


人IgG1-κ


免疫原


白细胞介素-8。99的结构域28-99(1-20信号肽,CPR 21-99)。


特异性


特异性已在ELISA中测试(图1)。


纯度


纯化蛋白A。


免责声明


该抗体仅供研发使用。不用于诊断或


治疗程序。


注意事项


一。对于专业用户。


2。与任何来自生物源的产品一样


应使用处理程序。


三。该产品可用于不同的技术和


结合不同的样品类型和材料,


因此,每个实验室应验证


应用测试系统。


抗体的制备


使用提供的抗体。


储存/稳定性


储存于-20°C。首次使用后,储存于4°C。避免重复冻融循环。


应用指南


酶联免疫吸附试验:1:1000-1:5000


其他用途:由于用途不同,最佳工作稀释度


应在适当的分析中测定产品的含量。


除非实际测试系统的稳定性已经确定,否则


建议在使用前立即稀释产品。


关联


IL-8是一种趋化因子,可吸引中性粒细胞、嗜碱性粒细胞和tcell,但不吸引单核细胞。它也参与中性粒细胞的激活。它是


在炎症反应中从几种细胞中释放出来


刺激。IL-8(6-77)对中性粒细胞有5-10倍的活性


活化,IL-8(5-77)增加了中性粒细胞活化和


IL-8(7-77)对受体CXCR1和CXCR2有较高的亲和力


分别与IL-8(1-77)比较。


1个


图1:ELISA测定抗IL8(MQR2.4401)的特异性。抗体储备1.28 mg/ml)


在含有0.05%吐温-20和1%牛血清白蛋白的PBS中稀释后,对人白细胞介素-8(蓝色)进行检测


以及非靶蛋白(红色)。



Product Name

Monoclonal Human anti-IL8 Immunoglobulin

CAT No.

MQR 2.4401

LOT No.

18313

Quantity

100 μg

Edition: September 11, 2019

Intended use

This product is for research use only. NOT for use in diagnostic or

therapeutic procedures.

This product is tested for use in enzyme-linked immunosorbent assay

(ELISA).

Reagent provided

The antibody is supplied in PBS.

Isotype

Human IgG1κ

Immunogen

Interleukin-8. Domain 28-99 of 99 (1-20 signal peptide, CPR 21-99).

Specificity

Specificity has been tested in ELISA (figure 1).

Purity

Protein A purified.

Disclaimer

The antibody is for R&D use only. NOT for use in diagnostic or

therapeutic procedures.

Precautions

1. For professional users.

2. As with any product derived from biological sources, proper

handling procedures should be used.

3. The product may be used in different techniques and in

combination with different sample types and materials,

therefore each individual laboratory should validate the

applied test system.

Preparation of the antibody

Use antibody as supplied.

Storage/Stability

Store at -20°C. After first time use, store at 4°C. Avoid repeated freezethaw cycles.

Application guidelines

ELISA: 1:1000 – 1:5000

Other applications: since applications vary, optimum working dilution

of the product should be determined in the appropriate assay.

Unless the stability in the actual test system has been established, it is

recommended to dilute the product immediately before use.

Relevance

IL-8 is a chemotactic factor that attracts neutrophils, basophils, and Tcells, but not monocytes. It is also involved in neutrophil activation. It is

released from several cell types in response to an inflammatory

stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil

activation, IL-8(5-77) has increased activity on neutrophil activation and

IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as

compared to IL-8(1-77), respectively.

1

Figure 1: Specificity of anti-IL8 (MQR2.4401), determined by ELISA. Antibody stock 1.28 mg/ml)

diluted in PBS containing 0.05% tween-20 and 1% BSA was tested on human interleukin-8 (in blue)

and non-target protein (in red).