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现在位置首页>实验室原料试剂耗材>化学试剂>材料科学>MQR2.601 anti-modified citrulline (clone C4)
MQR2.601	anti-modified citrulline (clone C4)
MQR2.601	anti-modified citrulline (clone C4)
  • MQR2.601	anti-modified citrulline (clone C4)

MQR2.601 anti-modified citrulline (clone C4)

产品报价:询价

更新时间:2023/4/3 18:11:18

地:美国

牌:ImmunoPrecise

号:MQR2.601

厂商性质: 生产型,

公司名称: 世联博研(北京)科技有限公司

产品关键词: human anti-modified citrulline   anti-modified citrulline (clon   MQR2.601   MQR2.601 anti-modified citrull   modified citrulline  

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品名


单克隆人抗修饰瓜氨酸


(AMC),免疫球蛋白,克隆C4


货号。


MQR 2.601-100号


批号。


15322个


数量


100微克


版本:2015年12月22日


预期用途


本产品仅供研究使用。不用于


诊断或治疗程序。


该产品经测试可用于酶联免疫吸附


ELISA法和Western Blot法。


提供试剂


抗体以PBS形式提供


同型


人IgG1λ


免疫原


2,3修饰瓜氨酸肽-


丁二酮单肟和安替比林。


特异性


特异性已在ELISA(图1)和WB(图


2) 是的。识别经修饰的瓜氨酸蛋白


与2,3-丁二酮单肟和安替比林无关


邻近的氨基酸序列。


纯度


纯化蛋白A。


注意事项


一。对于专业用户。


2。就像从生物来源得到的任何产品一样,


应采用适当的处理程序。


三。该产品可用于不同的技术和


结合不同的样品类型和材料,


因此,每个实验室都应验证


应用测试系统。


抗体的制备


使用提供的抗体。


存储说明


储存于2-8°C。


应用指南


酶联免疫吸附试验:0.08–0.4微克/毫升


白细胞:1微克/毫升


除非实际测试系统的稳定性


已确定,建议稀释产品


立即使用。


关联


此抗体用于检测瓜氨酸


含有蛋白质的。氨基酸瓜氨酸是由


精氨酸的翻译后修饰


肽基精氨酸脱氨酶(PADs;MQ16.201和


MQ16.203)。抗瓜氨酸抗体


类风湿中检测到蛋白质(如组蛋白)


关节炎患者。


图1:AMC免疫球蛋白(MQR2.601)的特异性,通过酶联免疫吸附试验测定。


在含有0.05%吐温-20和1%牛血清白蛋白的PBS中稀释至0.4微克/毫升的抗体


不同修饰的瓜氨酸肽及其未修饰肽的检测



Product Name

Monoclonal Human Anti-Modified Citrulline

(AMC), Immunoglobulin, clone C4

CAT No.

MQR 2.601-100

LOT No.

15322

Quantity

100 μg

Edition: December 22, 2015

Intended use

This product is for research use only. NOT for use in

diagnostic or therapeutic procedures.

This product is tested for use in enzyme-linked immunosorbent

assay (ELISA) and Western Blot (WB).

Reagent provided

The antibody is supplied in PBS

Isotype

Human IgG1λ

Immunogen

Citrulline-containing peptide modified with 2,3-

butanedione monoxime and antipyrine.

Specificity

Specificity has been tested in ELISA (figure 1) and WB (figure

2). Recognizes citrulline-containing proteins modified

with 2,3-butanedione monoxime and antipyrine regardless

of amino acid sequences.

Purity

Protein A purified.

Precautions

1. For professional users.

2. As with any product derived from biological sources,

proper handling procedures should be used.

3. The product may be used in different techniques and in

combination with different sample types and materials,

therefore each individual laboratory should validate

the applied test system.

Preparation of the antibody

Use antibody as supplied.

Storage instructions

Store at 2-8°C.

Application guidelines

ELISA: 0.08 – 0.4 μg/ml

WB: 1 μg/ml

Unless the stability in the actual test system has been

established, it is recommended to dilute the product

immediately before use.

Relevance

This antibody is developed for the detection of citrulline

containing proteins. The amino acid citrulline is generated by

posttranslational modification of arginine by

peptidylarginine-deiminases (PADs; MQ16.201 and

MQ16.203). Antibodies directed to citrulline containing

proteins (e.g. histones) are detected in rheumatoid

arthritis patients.

Figure 1: Specificity of AMC Immunoglobulin (MQR2.601), determined by ELISA.

Antibody diluted to 0.4 μg/ml in PBS containing 0.05% tween-20 and 1% BSA was

tested on various modified citrulline-containing peptides and their non-modified