ABP55104 Lunatic Fringe Polyclonal Antibody 北京供应
产品报价:1540元
更新时间:2017/10/17 11:58:01
产地:北京
品牌:Abbkine
型号:ABP55104
厂商性质: 生产型,贸易型,服务型,
公司名称: 北京方程嘉鸿科技有限公司
王洁 : (13161895572) (010-82833221)
(联系我时,请说明是在来宝网上看到的,谢谢!)产品报价:1540元
更新时间:2017/10/17 11:58:01
产地:北京
品牌:Abbkine
型号:ABP55104
厂商性质: 生产型,贸易型,服务型,
公司名称: 北京方程嘉鸿科技有限公司
王洁 : (13161895572) (010-82833221)
(联系我时,请说明是在来宝网上看到的,谢谢!)ABP55104 Lunatic Fringe Polyclonal Antibody 北京供应
背景资料 :ABP55104 Lunatic Fringe Polyclonal Antibody 北京供应 LFNG is a member of the fringe gene family which also includes radical and manic fringe genes. They all encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This gene product is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Multiple transcript variants encoding different isoforms have been found for this gene.
蛋白别名为:LFNG; Beta-1; 3-N-acetylglucosaminyltransferase lunatic fringe; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase;基因ID为:3955;蛋白质ID:Q8NES3
ABP55104 Lunatic Fringe Polyclonal Antibody 北京供应
应用类型 :WB,ELISA
补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.
免疫原 :合成多肽:the Internal region of human Lunatic Fringe. at AA rangle: 90-170
来源宿主 :兔
反应性 :人,小鼠,大鼠