Bio-Flash是一款全自动化学发光仪，用于靶抗原确认实验。

Bio-Flash使得CLIA应用于自身免疫性疾病检测变为现实，不仅大大缩短检测耗时，而且大大提高检测结果的敏感性和特异性，大大扩展检测项目的线性范围，提供无与伦比的定量检测结果。

美国INOVA公司的自免检测整体自动化系统能给广大的自免实验室带来方便，让自身免疫疾病检测早日实现自动化，标准化。

BIO-FLASH

Fully automated, benchtop, random access and multiparametric immunoassay system.

BIO-FLASH is a fully automated, benchtop, random access and multiparametric immunoassay system.

Magnetic particle separation with flash chemiluminescent detection delivers exceptional clinical performance, offering immunoassays with high sensitivity and extremely large dynamic ranges.

Simple to use

• No reagent handling: self-contained, ready-to-use,
  precalibrated reagent cartridges

• Integrated barcode reader for reagent cartridges and samples

• Cartridges refrigerated at 4°C and stable up to more than 2 months onboard

• Calibrators & control barcoded

• Easy rack-loading system accomodates up to 30 samples

• Windows interface and touchscreen, flat LCD monitor with intuitive prompts

Fast and efficient

• Up to 20 reagent cartridges onboard

• Available 24 hours/day, 7 days/week

• Up to 64 tests/hour

• Time to first result: ~ 30 minutes

• Random or batch sample processing

• Continuos sample loading

• Clot detection

• STAT function

Highly accurate

• Automated chemiluminiscent technology boosts accuracy and sensitivity

• Each assay is precalibrated to assure accuracy and standardization

• High sensitivity (isoluminol)

• No optical interference

Reliability

• Automatic reflex testing

• Automatic results validation

• Westgard multi-rules

• Levey-Jennings charts

1 Safety Covers: The sample and reagent modules are protected

by lockable covers, that increase operation safety and reduce the

effect of the external environment on the instrument, minimizing

the evaporation of samples and reagents and helping to maintain

temperature control. The BIO-FLASH instrument will not operate

if any of the access covers remain open.

2 Cuvette Loader Module: The exclusive cuvette loader system

can contain up to 280 disposable cuvettes organized in 20 columns

with 14 cuvettes per column. These columns are automatically

separated into individual cuvettes and transferred into the

incubator module. The cuvette loader controls the number of

available cuvettes on-board and displays a warning message

when the supply is low. New cuvettes can be added to this module

at any time.

3 Sample Module: The sample carrousel is designed to hold up

to 6 rack sectors, each one capable of accommodating 5 sample

tubes, providing a total capacity of 30 samples on-board.

A variety of primary or aliquot sample tubes, cups and false

bottom tubes can be accommodated in the rack sectors.

The flexibility of the instrument makes it possible to work with

STAT, automated rerun, reflex tests and calculated testing

minimizing operator handling.

The sample rack sectors configuration allows continuous sample

loading, which facilitates workflow efficiency.

4 Reagent Module: Up to 20 reagent cartridges can be held

in the reagent carrousel, which is cooled to 4oC.

The reagent cartridges are carried by the carrousel to designated

locations where the reagent pipettor can operate.

The reagent module mixes the innermost vial of the cartridge to

ensure homogenization of magnetic particles while the reagent

is aspirated. This ensures exceptional precision in result generation.

5 Reagent Cartridges: The innovative reagent cartridge includes

all necessary reagents in four sealed tubes with a piercing cover.

To start using the reagents, simply push the cover, which opens

the tube’s seal. Once this is done, reagent cartridges are ready

to be inserted into the instrument and ready for operation.

The reagent cartridge cover also has a mobile system that is

only opened by the instrument when the reagent probe is ready

to pipette one of the reagents. The rest of the time it is closed.

This reduces reagent evaporation and dust contamination and,

together with the refrigeration system, provides excellent on board

reagent stability.

Reagent cartridges have a barcode which includes the Master

Calibration Curve, used for calibrating the entire reagent lot. This

Master Calibration Curve together with reagent stability reduces

reagent usage and hands-on operation time.

6 Sample Probe: Used to pipette samples and diluents.

The sample probe is equipped with a Clot Detection system based

on pressure differential technology. This ensures accurate sampling

and prevents false negative results due to fibrin clots. The needle

also has a Liquid Level Sensor including Crash Detection.

The sample probe is coated with a ceramic compound which,

together with the cleaning solution, reduces the carry-over below

0.1 ppm.

7 Reagent Pipettor: Used for aspirating and dispensing

intermediate reagents and the reagent with magnetic particles.

This probe is also coated with a ceramic compound to prevent

carry-over contamination between reagents, and has a Liquid

Level Sensor including Crash Detection.

8 Distributor/Incubator: The distributor module provides slots

for up to 46 reaction cuvettes, and incubates all the reaction

steps to 37oC. The distributor’s rotation system ensures a quickchange

of the cuvette position between the cuvette loader,

MagWash station, dispense positions and Luminometer.

9 Magnetic Wash Station: The MagWash station is an arcshaped

array with 8 wash stations located inside the incubator

module. This station carries out the separation of magnetic

particles from other reaction liquids.

10 Luminometer: The Luminometer receives the processed

samples and activates them with trigger reagents to obtain a

flash chemiluminescent signal. The measurement device is a

photomultiplier tube that translates light into electrical signals