iCyte®自动成像血细胞计数,iCyte® Automated Imaging Cytometer

First introduced in 2002, the iCyte® Automated Imaging Cytometer is designed to meet the demand in the biotechnology and pharmaceutical markets for automated high-content cellular analyzers which provide for higher throughput. Among its many advanced features is the ability to precisely measure cellular DNA content – essential in toxicological studies – and simultaneously combine the information gathered from these measurements with other molecular markers and cell morphology. The iCyte’s unique software offers unprecedented flexibility in data analysis.

While the instrument relies on the basic laser scanning technology, its unique features include:

Morphological and quantitative features for very high content cell-based analysis Multiple lasers and photomultipliers for flexible dye combinations Compatibility with a variety of carriers, including microtiter plates and microscope slides, for unsurpassed specimen flexibility Automated or manual operation modes Cellular and tissue specimen analysis Open assay development and data reporting platforms to accommodate rapidly changing discovery needs

iCyte enables fully automated, walk-away analysis of cellular specimens. New features include:

Robotic specimen loader with 45-tray capacity, allowing walk-away experimental analysis Optional iNovator™ Application Development Toolkit, enabling fully automated tissue identification and scan region selection. Accurate quantitative measurement of tissue fluorescence is enhanced by novel background fluorescence subtraction techniques Flexible iBrowser™ Data Integration software, facilitating post-acquisition analysis of large volumes of generated data

For more information about iCyte, see the iCyte Specification Sheet . (PDF, 478KB) For information about iCyte software, see iCyte or iCys Cytometric Analysis Software. In addition to the standard iCyte configuration, there are a number of accessories and software options available for this instrument.

 美国CompuCyte Corporation 是一家未公开上市公司，总部位于马萨诸塞州剑桥。该公司是开发用于生命科学研究、药物安全、毒物学研究以及临床试验的细胞分析仪器的领导者。该公司的 iCyte(R)、iCys(R) 和 iColor(TM) 血细胞计数器使细胞与组织样本的定量流式图像分析成为可能。

CompuCyte develops Laser Scanning Cytometry products for cell-based and tissue analysis, using advances in optics, computer technology, and imaging techniques. CompuCyte’s products provide life scientists, pharmaceutical researchers, and clinical laboratory professionals with unique high-information content analysis and reporting capabilities for discovery and objective characterization of the biophysical and biochemical cellular processes that define the normal and disease states.

Founded by Dr. Louis Kamentsky, internationally recognized for his pioneering work in the field of flow cytometry, CompuCyte’s Laser Scanning Cytometry provides life science researchers with the ability to undertake high-content analysis of cell and tissue specimens on a solid substrate, not feasible with any other product.

CompuCyte ’s platform technology, Laser Scanning Cytometry, has applications in basic life science research, drug discovery, and molecular pathology. The Company’s products based on this technology include the iCyte™ Automated Imaging Cytometer, the iCys™ Research Imaging Cytometer, the LSC® Laser Scanning Cytometer, and our revolutionary new development, the iColor™ Fluoro-Chromatic Imaging Cytometer. When combined with iBrowser™ Data Integration Software and the iNovator Application Development Toolkit, CompuCyte’s family of instruments provide unmatched flexibility in specimen formats and automation options, combined with analytical performance (quantitative cell-based analysis) and specimen visualization.

iCyte, using an inverted microscope platform, automates higher-volume, high-content cellular analysis performed on a variety of carriers, including microtiter plates and microscope slides. When combined with the optional robotic specimen loader, iCyte allows full walk-away analysis in areas of research that call for processing large numbers of samples, such as drug toxicity or biomarker discovery often performed on multiple tissue slides or with tissue microarrays.
iCys allows specimen visualization through its fully-configured microscope along with both laser scanning and brightfield visualization capabilities. iCys is quickly becoming the analytic tool of choice for life science research.
iColor combines the advantages of flow cytometry, fluorescence image analysis, and immunohistochemistry in one unique system. iColor allows simultaneous analysis of both fluorescent and chromatic staining in the same specimens, opening new applications to the power of quantitative analysis.
The Company’s prestigious customer base includes the top scientific and clinical research institutions (both governmental and universities), leading biotechnology and pharmaceutical companies, and the most highly regarded hospitals and reference laboratories worldwide.