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可得然胶Curdlan
可得然胶Curdlan
  • 可得然胶Curdlan

可得然胶Curdlan

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更新时间:2012/8/24 15:27:29

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可得然胶Curdlan
Wako
 
Grade: for Biochemistry 
Regulation / Hazardous:  
Storage condition: Keep at RT.
Manufacturer: Wako 

Summary
 
This product is for research use only. Do not administer it to human.

Curdlan is produced as a water-insoluble polysaccharide by the soil bacterium, Alcaligenes faecalis var. myxogenes, and was discovered by Dr. T. Harada at the Institute of Scientific and Industrial Research, Osaka University. One of the characteristics of Curdlan is that when the suspension is heated, it becomes a thermally irreversible gel. Curdlan is used as gel filtration support, affinity chromatography support, immobilized enzyme support, starch jelly and low calorie food or a material hardening substance. Curdlan has gained attention as a research material for gelation mechanism or as a basic material for anti-tumor polysaccharide research. 
 
Appearance: White Powder
Structure: Straight chain without branch
Solubility: Insoluble in water and many organic solvents. Freely soluble in aqueous alkaline solution. Soluble in DMSO and formic acid.
Specific Rotation [A]20/D: +30.0 ~ +35.0
Gel stability: pH 2.0 ~ 9.5 (max. gel strength: pH 2 ~ 3)  
USAGE:
Gel filtration and affinity chromatography; Immobilized enzyme support; Research for mechanism of gelation; Research for anti-tumor glucans CM-CURDLAN [Carboxymethyl-beta-1,3-D-glucan]
CM-Curdlan is water soluble beta-1,3-glucan which modified by carboxymethylation at 40 ~ 80% substitution from Curdlan.  
REFERENCES:

T. Harada: Polysaccharides In Food, Butterworths In England, 283 (1979).
Harada, T., Masada, M., Fujimori, K. and I. Maeda, I.: Agric. Biol. Chem., 30, 196 (1966).
Harada, T., Misaki, A. and Saito, H.: Arch. Biochem. Biophys., 124, 292 (1968).
Hisamatsu, M., Ott, I., Amemura, A., Harada, T., Nakanishi, I. And K. Kimura.: J. Gen. Microbiol., 103, 375 (1977).
Maeda, I., Saito, H., Masada, M., Misaki, A. and Harada, T.: Agric. Biol. Chem., 31, 1184 (1967).
Konno, A., Azechi, Y. and Kimura, H.: Agric. Biol. Chem., 43, 101 (1979).
Murooka, Y., Yim, M., Yamada, T. and Harada, T.: Biochim. Biophys. Acta., 485, 134 (1977).
Kimura, H., Moritaka, S. and Misaki, M.: J. Food Science, 38, 668 (1973).
Takeda, H., Yasuoka, N., Kasai, N., and Harada, T.: Polymer Journal, 10, 365 (1978).
Marchessault, R. H. and Y. Deslandes: Carbohyd. Res., 75, 231 (1979).
Fulton, W. S. and E. D. T. Atkins: ACS Symposium Series, 141, 385 (1980).
Saito, H., Ohki, T. and Sasaki, T.: Biochemistry, 16, 908 (1977).
Harada, T., Koreeda, A., Sato, S. and N. Kasai: J. Electron Microsc., 28, 147 (1979).
Sasaki, T., Abiko, N., Sugino, Y. and Nitta, K.: Cancer Res., 38, 379 (1978).
Sasaki, T., Abiko, N., Nitta, K., Takasuka, N. and Sugino, Y.: European J. Cancer, 15, 11 (1979).
  
Synonym beta-1,3-Glucan 
  Molecular Formula (-C6H10O5-)n 
Appearance:  White - slightly brown, powder 
  Specific Rotation:  +30 - +35 degrees(D/20 degrees C) (c=1, dil. NaOH sol.) 
*********************************************************************
CM-Curdlan
Wako
 
Grade: for Biochemistry 
Regulation / Hazardous:  
Storage condition: Keep at RT.
Manufacturer: Wako 

Summary
 
CM-CURDLAN is water soluble 1,3-beta-glucan which is modified by carboxymethylation at 40-80% substitution from curdlan.  

Synonym CM-curdlan
Carboxymethyl Curdlan
Carboxymethyl-beta-1,3-D-glucan 
  CAS NO. 114732-86-4 
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