ApplicationsE, WB, IHC
Species reactivityH, M, R, Other
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4. Antibody was purified by Protein-G affinity chromatography.
The CD3 antibody recognizes the 17-19 kD ε-chain of CD3 within the CD3 antigen/T cell antigen receptor (TCR) complex. The CD3 antigen is expressed in the cell cytoplasm during the early stage of T cell development and is expressed on the cell membrane at the late stage. CD3 antigen is displayed on 60-80% of normal peripheral blood lymphocytes and 60-70% of thymocytes and plays an important role in signal transduction after antigen recognition by TCR. NK cells also express the CD3 antigen in the cytoplasm.
T-cell surface glycoprotein CD3; T-cell surface antigen T3/Leu-4; CD3; T3
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD3 epsilon.
Store at -20°C. Product is guaranteed 6 months from the date of shipment.
|Cellular Antigens, Receptors & Channels, Immune System, Signaling Molecules & Interaction|