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CD3 (HIT3b) Antibody
CD3 (HIT3b) Antibody
  • CD3 (HIT3b) Antibody

CD3 (HIT3b) Antibody

产品报价:询价

更新时间:2019/5/24 9:21:05

地:美国

牌:abbiotec

号: 0.1mg

厂商性质: 生产型,贸易型,

公司名称: 深圳市豪地华拓生物科技有限公司

产品关键词:

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CD3 (HIT3b) Antibody

Mouse Monoclonal

Catalog Number

250935

Unit

0.1 mg

Price

$220.00

Isotype

Mouse IgG1

Applications

E, IHC, FC

Species reactivity

H

Format

 

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

 

Description

The CD3 (HIT3b) antibody recognizes the 17-19 kD ε-chain of CD3 within the CD3 antigen/T cell antigen receptor (TCR) complex. The CD3 antigen is expressed in the cell cytoplasm during the early stage of T cell development and is expressed on the cell membrane at the late stage. CD3 antigen is displayed on 60-80% of normal peripheral blood lymphocytes and 60-70% of thymocytes and plays an important role in signal transduction after antigen recognition by TCR. The clone HIT3a has a strong mitogenic effect at ng level on T lymphocyte proliferation in soluble or immobilized conditions and has an immunosuppressive effect at high dose. Conversely, the clone HIT3b has a strong mitogenic effect on T lymphocytes proliferation only under immobilized condition.


Product Citations

 

Shen DC. et al. 1993. ACTA Academia Medicinae Sinicae. 15(3):157

Schlossman S. et al., eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. P246, Oxford University Press, New York.

Tadamitsu K. et al., eds. 1997. Leucocyte Typing VI: White Cell Differentiation Antigens. P49-52, 113-114  Garland Publishing, Inc., New York.

 

Recommended Products

250991 CD3 (HIT3b) Antibody, FITC
251047 CD3 (HIT3b) Antibody, PE
 

Alternate Names

T-cell surface glycoprotein CD3; T-cell surface antigen T3/Leu-4; CD3; T3

Accession No.

P07766
 

Clonality

HIT3b

Application Notes

 

Purified antibody is suitable for immunohistochemistry with acetone-fixed frozen sections.

E: 1:500-1:1,000

FACS: 1:200-1:1,000

IHC: 1:200-1:500

 

 

Storage

 

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

 

Cellular Antigens,  Immune System, Signaling Molecules & Interaction
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For research use only, not for diagnostic or therapeutic procedures.