CD3 (HIT3a) Antibody
产品报价:询价
更新时间:2020/1/16 9:04:48
产地:美国
品牌:abbiotec
型号:2ml
厂商性质: 生产型,贸易型,
公司名称: 深圳市豪地华拓生物科技有限公司
丁先生 : (13265824656) (0755-26055215)
(联系我时,请说明是在来宝网上看到的,谢谢!)产品报价:询价
更新时间:2020/1/16 9:04:48
产地:美国
品牌:abbiotec
型号:2ml
厂商性质: 生产型,贸易型,
公司名称: 深圳市豪地华拓生物科技有限公司
丁先生 : (13265824656) (0755-26055215)
(联系我时,请说明是在来宝网上看到的,谢谢!)http://www.abbiotec.com/antibodies/cd3-%28hit3a%29-antibody-0请您点击此链接查看产品说明书
Catalog Number250990 Unit2 ml Price$275.00 IsotypeMouse IgG2aApplicationsE, IHC, FCSpecies reactivityHFormat
Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
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DescriptionThe CD3 (HIT3a) antibody recognizes the 17-19 kD ε-chain of CD3 within the CD3 antigen/T cell antigen receptor (TCR) complex. The CD3 antigen is expressed in the cell cytoplasm during the early stage of T cell development and is expressed on the cell membrane at the late stage. CD3 antigen is displayed on 60-80% of normal peripheral blood lymphocytes and 60-70% of thymocytes and plays an important role in signal transduction after antigen recognition by TCR. The clone HIT3a has a strong mitogenic effect at ng level on T lymphocyte proliferation in soluble or immobilized conditions and has an immunosuppressive effect at high dose. Conversely, the clone HIT3b has a strong mitogenic effect on T lymphocytes proliferation only under immobilized condition. NK cells also express the CD3 antigen in the cytoplasm, making the CD3 (HIT3a) antibody a helpful tool for analyzing the development relationship and the common precursor of both T cells and NK cells. Product Citations
Shen DC. et al. 1993. ACTA Academia Medicinae Sinicae. 15(3):157 Schlossman S. et al., eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. P246, Oxford University Press, New York. Tadamitsu K. et al., eds. 1997. Leucocyte Typing VI: White Cell Differentiation Antigens. P49-52, 113-114 Garland Publishing, Inc., New York.
Recommended Products250934 CD3 (HIT3a) Antibody Alternate NamesT-cell surface glycoprotein CD3; T-cell surface antigen T3/Leu-4; CD3; T3 Accession No.P07766 ClonalityHIT3a Application Notes
FACS with whole blood: 100 μl blood + 20 μl antibody; FACS with cells: 10E6 cells + 20 μl antibody. FACS: 1:200-1:1,000
Storage
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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Cellular Antigens, Immune System, Signaling Molecules & Interaction |
For research use only, not for diagnostic or therapeutic procedures.