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CD2AP Antibody
CD2AP Antibody
  • CD2AP Antibody

CD2AP Antibody

产品报价:询价

更新时间:2019/5/17 8:54:08

地:美国

牌:abbiotec

号: 0.1mg

厂商性质: 生产型,贸易型,

公司名称: 深圳市豪地华拓生物科技有限公司

产品关键词:

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CD2AP Antibody

Rabbit Polyclonal

Catalog Number

251169

Unit

0.1 mg

Price

$245.00

Isotype

Rabbit Ig

Applications

E, WB, IHC, IP

Species reactivity

H, M, R

Format

 

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

 

Description

CD2-associated protein (CD2AP) is an adapter protein between membrane proteins and the actin cytoskeleton. CD2AP plays a role in receptor clustering and cytoskeletal polarity in the junction between T-cells and antigen-presenting cells. CD2AP anchors the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. CD2AP is also required for cytokinesis. Defects in CD2AP are the cause of susceptibility to focal segmental glomerulosclerosis type 3 (FSGS3), a renal pathology defined by the presence of segmental sclerosis in glomeruli and resulting in proteinuria, reduced glomerular filtration rate and edema.


Alternate Names

CD2AP; CD2-associated protein; Cas ligand with multiple SH3 domains; Adapter protein CMS

Accession No.

Q9Y5K6
 

Antigen

 

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD2AP.

 

Application Notes

 

E: 1:500-1:1,000
WB: 1:100-1:500
IHC: 1:100-1:500
IP: 1:100-1:500

 

Storage

 

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

 

Cytoskeleton Proteins,  Infectious Diseases
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For research use only, not for diagnostic or therapeutic procedures.