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CD276 (6A1) Antibody
CD276 (6A1) Antibody
  • CD276 (6A1) Antibody

CD276 (6A1) Antibody

产品报价:询价

更新时间:2019/7/15 9:12:56

地:美国

牌:abbiotec

号: 0.1ml

厂商性质: 生产型,贸易型,

公司名称: 深圳市豪地华拓生物科技有限公司

产品关键词:

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CD276 (6A1) Antibody

Mouse Monoclonal

Catalog Number

253062

Unit

0.1 ml

Price

$308.00

Isotype

Mouse IgG1

Applications

WB, IHC, IF

Species reactivity

H

Format

 

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

 

Description

Costimulatory B7 molecules (e.g., B7-1, or CD80; MIM 112203) signal through CD28 (MIM 186760) family molecules such as CD28, CTLA4 (MIM 123890), and ICOS (MIM 604558). May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.


Alternate Names

B7H3; B7-H3; 4Ig-B7-H3; CD276

Accession No.


 

Clonality

6A1

Antigen

 

Purified recombinant fragment of human CD276 expressed in E. coli.

 

Application Notes

 

WB: 1:200-1:1000;IHC: 1:200-1:1000
IF: 1:200-1:1000

 

Storage

 

Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.

 

 
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For research use only, not for diagnostic or therapeutic procedures.