S1523 XL765(SAR245409)现货
产品报价:询价
更新时间:2012/7/19 9:42:10
产地:北京
品牌:selleck
型号:S1523
厂商性质: 生产型,贸易型,服务型,
公司名称: 北京乐博生物科技有限公司
刘小姐 : (13621283223) (4006130504)
(联系我时,请说明是在来宝网上看到的,谢谢!)产品报价:询价
更新时间:2012/7/19 9:42:10
产地:北京
品牌:selleck
型号:S1523
厂商性质: 生产型,贸易型,服务型,
公司名称: 北京乐博生物科技有限公司
刘小姐 : (13621283223) (4006130504)
(联系我时,请说明是在来宝网上看到的,谢谢!)
该产品另有其他规格及报价,欢迎来电垂询。
Technical Data:
M.Wt: 599.66
Formula: C31H29N5O6S
Solubility: Unknown
Purity: >99%
Storage: at -20℃ 2 years
CAS No.: 1123889-87-1
Biological Activity:
XL-765(SAR245409) is a mixed mTOR/PI3k inhibitor with IC50 of 157, 39, 113, 9 and 43 nM for mTOR, p110α, β, γ and δ, respectively. It is an orally available small molecule that has been shown in preclinical studies to selectively inhibit the activity of phosphoinositide-3 kinase (PI3K) and mammalian target of rapamycin (mTOR). In preclinical studies, XL765 slowed tumor growth or caused tumor shrinkage in multiple preclinical cancer models, including breast, lung, ovarian, and prostate cancers, and gliomas. XL765 has also been shown to enhance the anti-tumor effects of several chemotherapeutic agents in preclinical cancer models. [1]
北京乐博生物科技有限公司代理供应美国Selleck chem公司全线产品。