乐博现货供应美国ProSci凋亡相关--FLASH (CT) antibody
刘小姐 : (13621283223) (4006130504)
(联系我时,请说明是在来宝网上看到的,谢谢!)刘小姐 : (13621283223) (4006130504)
(联系我时,请说明是在来宝网上看到的,谢谢!)北京乐博生物科技有限公司是美国ProSci授权一级代理商,供应其全线产品涵盖了细胞凋亡、信号传导、肿瘤、免疫、细胞生物、神经生物和传染病等领域。产品应用于ELISA、WB、IHC、FACS等,为您的实验提供多样的检测手段,产品应用文献发表在PNAS、Cell research、Blood……使用广泛。
抗体信息如下:
A novel mammalian CED-4 homologous was recently identified and cloned in mouse (1) and human (2) and designated FLASH (for FLICE-associated huge protein). FLASH is involved in Fas induced apoptosis. It is recruited to Fas after the receptor cross-linking. Overexpression of wild type of FLASH facilitates and its dominant negative form inhibits Fas induced apoptosis. FLASH interacts with the DEDs of caspase-8 and FADD through the DED-like domain of FLASH and mediates activation of caspase-8 (1). There are parallels between FLASH and Apaf-1/CED-4 although there are arguments against their structural similarity (1,2). FLASH is widely expressed.
FLASH (CT), FLASH
DescriptionLeft: Western blot analysis of FLASH in HeLa whole cell lysate with FLASH antibody at 0.5 μg/ml.Below: Immunocytochemistry of FLASH in HeLa cells with FLASH antibody at 10 μg/ml. |
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FLASH antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy-terminus of human FLASH which differ from those of mouse by one amino acid.
Affinity chromatography purified via peptide column
This is a polyclonal antibody.
FLASH antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Human FLASH (C-Terminus) Peptide (Cat. No. 2271P)
FLASH antibody can be used for detection of FLASH by Western blot at 0.25 to 0.5 μg/ml. An approximate 220 kDa band can be detected.
E, WB, ICC
Antibody is supplied in PBS containing 0.02% sodium azide.
Cat. No. 2271P - FLASH Peptide
FLASH antibody can be stored at 4?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
H
5533376
AF165161
(CT) Homolog of CED4
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