乐博现货供应美国ProSci凋亡相关--Caspase-9 (IN1)antibody
刘小姐 : (13621283223) (4006130504)
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(联系我时,请说明是在来宝网上看到的,谢谢!)北京乐博生物科技有限公司是美国ProSci授权一级代理商,供应其全线产品涵盖了细胞凋亡、信号传导、肿瘤、免疫、细胞生物、神经生物和传染病等领域。产品应用于ELISA、WB、IHC、FACS等,为您的实验提供多样的检测手段,产品应用文献发表在PNAS、Cell research、Blood……使用广泛。
抗体信息如下:
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. A novel member in the caspase family was recently identified and designated ICE-LAP6, Mch6, and Apaf-3 (1-3). Caspase-9 and Apaf-1 bind to each other, which leads to caspase-9 activation (3). Caspase-9 is also activated by granzyme B and CPP32 (1,2). Activated caspase-9 cleaves and activates caspase-3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis (3). Caspase-9 play a central role in cell death induced by a wide variety of apoptosis activators including TNFα, TRAIL, anti-CD-95, FADD, and TRADD (4). Caspase-9 is expressed in a variety of human tissues (1,2).
Caspase-9 (IN1), Mch6/ Apaf-3, Casp-9
DescriptionLeft: Western blot analysis of caspase-9 in HeLa whole cell lysate with caspase-9 antibody at 1:1000 dilution. |
Caspase-9 antibody was raised against a peptide corresponding to amino acids 41 to 56 of human caspase-9 .
Affinity chromatography purified via peptide column
This is a polyclonal antibody.
Caspase-9 antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Human Caspase-9 (Intermediate Domain 1) Peptide (Cat. No. 2071P)
Caspase-9 antibody can be used for detection of caspase-9 by Western blot at 1:1000 to 1:2000 dilution. A 46 kDa band should be detected. It has no cross response to other members in caspase family.
E, WB
Antibody is supplied in PBS containing 0.02% sodium azide.
Cat. No. 2071P - Caspase-9 Peptide
Caspase-9 antibody can be stored at 4?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
H, M, R
28558771
P55211
(IN1) A new caspase
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