产品报价：询价
更新时间：2012/7/19 9:44:55
产地：美国
品牌：Selleck
型号：S1196
厂商性质： 生产型,贸易型,服务型,
公司名称： 北京乐博生物科技有限公司
刘小姐 : (13621283223) (4006130504)
（联系我时，请说明是在来宝网上看到的，谢谢！）北京乐博生物科技有限公司代理供应美国Selleck公司全线产品。原装进口，99%纯度！现货促销！
免费咨询热线：4006130504
公司网站：www.lab-bio.com
M.Wt: 296.4
Formula: C20H24O2
Solubility: Unknown
Purity: >99%
Storage: -20℃ 2 years
CAS No.: 107868-30-4
Biological Activity:
Exemestane is an irreversible, oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive breast cancer in postmenopausal women. [1]Its structure was related to the natural substrate androstenedione and it acts as a false substrate for the aromatase enzyme, an effect also known as "suicide inhibition."[1]The estrogen suppression rate for exemestane varies from 85% for estradiol (E2) to 95% for estrone (E1).[1]Exemestane was found to inhibit human placental aromatase with IC50 of 42 nM.[2]
