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APMSF hydrochloride BioChemica

价    格:询价

产    地:德国更新时间:2019/7/15 13:41:34

品    牌:AppliChem型    号:A0998

状    态:正常点击量:1165

18210960361
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北京西美杰科技有限公司

联 系 人:方丽初

电     话:010-88597838

传     真:010-88595011

等     级: (第 12年)

性     质:生产型,贸易型,服务型,

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APMSF hydrochloride BioChemica

A0998

Order No. Quantity
A0998,0010 10 mg
A0998,0050 50 mg
A0998,0100 100 mg


产品参数

Synonym 4-Amidinophenylmethanesulfonyl fluoride hydrochloride, p-APMSF 
Melting point 190 - 192°C (dec.) 
Formula C8H9FN2O2S · HCl 
M 252.69 g/mol 
CAS-No. 74938-88-8 
HS-No. 29252900 
Storage -20°C 
LGK 10 - 13 
Specification  
Assay (HPLC) min. 97 % 


产品介绍

(1)  Laura, R. et al. (1980) Biochemistry 19, 4859-4864
APMSF, ein irreversibler Inhibitor von Serin-Proteasen.
  (2)  Sueyoshi, T. et al. (1995) Mol. Cell. Biol. 15, 4158-4166
Untersuchung von ''Nuclear Factor NF2d9''.

Hinweis

APMSF is an irreversible inhibitor of plasma serine proteases (trypsin-like proteases), which are specific for the basic amino acid side chains lysine and arginine. If applied in equimolar ratios of enzyme and inhibitor, immediate, complete inhibition of trypsin and thrombin occurs. At a 5 to 10fold excess of inhibitor, factor Xa (bovine) and plasmin (human) will be inhibited. Acetylcholine esterase is insensitive.
APMSF is a more potent inhibitor than PMSF. Its effective concentration is 10 - 50 μM or 2.5 μg/ml, respectively (e. g. ref. 2). Stock solutions are prepared in water at concentrations of 1 - 5 mM. It is stable, when stored aliquoted at -20°C.



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