QIAGEN向发展中国家提供监测动物疾病针对性分子检测仪器
- QIAGEN2010年12月2日 13:23 点击:3587
凯杰(NASDAQ: QGEN; Frankfurt, Prime Standard: QIA)被联合国选定合作开展国际试点项目,为发展中国家提供针对传染性动物疾病的便携式快速分子诊断仪器。
凯杰的 ESE-Quant Tube Scanner 仪器为电池供电,仅重两磅,大小仅为一部台式电视,方便携带。在与联合国下属的粮农组织(FAO)和国际原子能机构(IAEA)合作的这次项目中,凯杰的针对性检测仪器能够在边远地区分离并分析病毒中的 DNA 和 RNA,无需取样到实验室进行化验,避免为运输样本造成的经济和时间的浪费。现场的快速诊断有助于在病源地对疾病爆发做出迅速反应,控制疫情进一步发展。
凯杰将初步为非洲、亚洲和南美洲的35个发展中国家的卫生机构提供50台此种仪器。这项为期三年的计划将评估此检测平台对传染性动物疾病的诊断,包括禽流感(H5N1),羊小反刍兽疫(PPR),以及牛肺疫(CBPP)。这些动物疾病导致了巨大的经济损失并威胁着数百万人的食品供给。
凯杰将在2010年11月下半月开始提供这些分子检测仪器。根据项目成果情况,这项计划有可能扩展至多达十种家畜疾病的检测。这一计划也有可能在其他国家地区陆续实施。
凯杰一直以来保持科技领先,致力于研发医疗保健和应用检测(如兽医研究、食品安全、环境保护和生物防御)的创新针对性检测平台。这台仪器是凯杰2010年1月收购以生产研发便携式分子诊断仪器为专长的 ESE GmbH 后,对其先进技术的实际应用。由于分子诊断技术应用的日益增长,急救室、紧急护理、医院和现场需要快速导出结果的便携检测仪器和解决方案,因此这些技术也将在人类医疗保健方面起到日益重要的作用。
“作为全球样品制备和分析技术的领先者,凯杰一直走在将先进的便携技术应用于基因检测的前列。尤其是在一些发展中国家,由于针对性检测能够应用于医疗保健和农业需求,因此这些技术能够为改善社会水平和经济状况作出很大贡献。这项有关家畜疾病的联合国粮农组织与国际原子能机构联合项目和凯杰发起的旨在防治发展中国家女性子宫颈癌的 careHPV 活动,将帮助挽救更多生命并让更多人体验这项检测技术。”凯杰的战略联盟总监 Konrad Faulstich 博士指出,“我们为这个项目提供的筛查系统将推进凯杰的发展战略,提高在针对性检测领域的领先地位。我们非常荣幸我们的应用检测技术能够协助这项国际计划的完成,帮助检测家畜类传染性疾病。”
“我们认为分子兽医诊断在早期发现高传染性动物疾病中起到日益重要的作用,”维也纳负责此次项目的项目经理 Hermann Unger 博士解释道,“为了有效推行这项计划,我们必须依靠低价、高品质、便携和易操作的检测方法。只有用这种办法我们才能在现场获得可能爆发的疾病信息从而为联合国各成员国迅速采取监控措施。我们非常感谢凯杰公司的合作,提供了技术和后勤支持并研发出这个针对我们需求的高性能平台以控制这些毁灭性动物疾病。”
跨境动物疾病的传播尤其给发展中国家和地区造成很大困难。例如,禽流感的爆发不仅给亚洲、非洲和欧洲数百万的家禽带来毁灭性的破坏,其传染性也威胁到人类健康。1995年博茨瓦那爆发的一场牛肺疫导致了高达5亿美元的经济损失。世界范围内,超过10亿只羊存在感染小反刍兽疫的危险,这一数量占全球小反刍动物总数的60%。此次联合国粮农组织与国际原子能机构联合项目旨在运用凯杰的先进检测技术快速诊断并有效控制此类流行病的爆发。
凯杰创新的 ESE-Quant Tube Scanner 可以在任何地方使用。只需一个按钮,仪器就能基于等温核酸扩增技术的应用,无需实验室条件就可将样本中的病毒 DNA 或 RNA 复制并进行分析。在运行中它能保持高度敏感的即时测量,同时可对检测结果进行质量控制。这台便携仪器能在约30分钟内同时处理多达8个样本,分析结果可以直接导入台式电脑或笔记本。
关于凯杰
凯杰是一家荷兰控股公司,是全球领先的样品制备和检测技术供应商。样品制备技术用于从血液或组织等生物样品中分离和制备 DNA、RNA 以及蛋白。检测技术用于分析这些分离所得的生物分子。公司客户遍布分子诊断实验室、学术研究机构、制药及生物技术公司和应用检测客户,产品用于法医样本鉴定、动物或食品检验以及和制药过程控制。凯杰的检测技术包括全球现有的应用最广泛的分子诊断平台,该平台包括 digene HPV 检测,它被视为检测引发子宫颈癌的元凶—高危型人乳头状瘤病毒 (HPV) 的“金标准”,同时还包括一整套传染病检测和诊断的解决方案。凯杰在全球30多个地方拥有3600多名员工。更多关于凯杰的信息,请访问 http://www.qiagen.com/。
关于世界粮农组织和联合国
联合国粮农组织/国际原子能机构帮助联合国粮农组织和国际原子能机构的成员国将核技术和相关生物科技应用于研发可持续性食品安全的改进策略。
根据《美国证券法1933年修订版》第 27A 条及《美国证券交易法1934年修订版》第 21E 条的规定,本新闻稿中包含的某些陈述可能被视为前瞻性声明。本文中包含的任何有关凯杰产品、市场、战略或经营业绩(包括但不限于预期的经营业绩)的声明在一定程度上均为前瞻性的,这些声明基于目前的预期和假设,包含许多不确定因素和风险。这些不确定性和风险包括但不限于增长管理和国际运营(包括货币波动、监管程序和对物流的依赖等的影响)相关的风险;经营业绩以及业务部门之间分配情况的变动;应用检测市场、个人保健市场、临床研究市场和蛋白质组学市场、妇女健康/ HPV 检测市场、基于核酸的分子诊断市场、以及基因疫苗和基因治疗市场的商业发展情况;与客户、供应商和战略伙伴的关系的变化;竞争形势;技术领域快速或意料之外的变革;对凯杰产品的需求的波动(包括由于总体经济形势、客户融资的水平和及时性、预算及其他因素造成的波动);我们的传染性疾病产品组合获得监管机构核准的能力;改造凯杰产品以集成到综合性解决方案中和生产这类产品过程中所面临的困难; 凯杰识别新的需求并开发出相应的新产品、与竞争对手的产品差分出来并保护自己的产品的能力;市场对凯杰新产品的接受度;以及整合收购的技术和业务等。如需更多信息,请参阅凯杰已在美国证券交易委员会归档或已提交的报告中的论述。 Germantown, MD; Hilden, Germany; and Vienna, Austria, November 29, 2010 - QIAGEN (NASDAQ: QGEN; Frankfurt, Prime Standard: QIA) has been selected to contribute to the fight against infectious diseases in animals in emerging countries by supplying an international pilot project associated with the United Nations with portable devices to perform ultra-fast molecular testing in the field. The QIAGEN instruments, called ESE-Quant Tube Scanners, weigh just two pounds and are about the size of a desktop telephone. In conjunction with assays developed at the Joint FAO/IAEA Division, an effort of the United Nations' Food and Agriculture Organization (FAO) and the International Atomic Energy Agency (IAEA), these QIAGEN point-of-need detection systems can analyze DNA or RNA from viruses or bacteria even in remote settings, which eliminates the need for time-consuming sample shipments to central laboratories for testing. Getting immediate results will enable rapid reaction to contain outbreaks at the source. QIAGEN will initially supply up to 50 of these instruments to national health authorities in 35 emerging countries in Africa, Asia and South America. The three-year pilot project will evaluate a testing system for detecting Avian Flu (H5N1) in poultry, Peste des Petits Ruminants (PPR) in sheep and goats, and Contagious Bovine Pleuro-Pneumonia (CBPP), also known as lung plague, in cattle. These livestock diseases cause serious economic damage and threaten the food supplies of millions of people. QIAGEN began supplying the detection platforms in the second half of November 2010 as part of the commercial agreement. Depending on outcomes, the initiative allows for future expansion of the veterinary diagnostic portfolio to a total of 10 livestock diseases. Subsequent implementation in other geographic regions would then be possible. QIAGEN is expanding its technology leadership by developing novel point-of-need platforms for healthcare and applied testing (veterinary, food, environmental and biodefense). This device is an application of technologies from the January 2010 acquisition of ESE GmbH, which has pioneered the development and manufacturing of portable devices for molecular testing. These types of technologies are expected to play an increasingly important role in human healthcare, as growing use of molecular diagnostics is creating a need for rapid turnaround and portable solutions in emergency rooms, critical care, hospitals and field settings. "As the global leader in sample and assay technologies, QIAGEN is on the forefront of applying advanced portable devices for gene-based testing. Particularly in less developed countries, point-of-need testing can play a crucial role since these devices can be adapted to local healthcare and agricultural needs, allowing the benefits of modern technology to contribute to improving social and economic conditions. Initiatives such as the Joint FAO/IAEA Programme in veterinary diseases and QIAGEN's previously launched careHPV initiative to fight cervical cancer among women in developing countries have great potential for saving lives and expanding access," said Dr. Konrad Faulstich, Director of Strategic Alliances at QIAGEN. "The scanner system we are supplying in the FAO/IAEA initiative advances our strategy to expand QIAGEN's leadership in point-of-need systems. We are very pleased that our applied testing technologies are assisting the international drive against infectious diseases in livestock." "We see molecular veterinary diagnostics as increasingly important to early detection of highly contagious diseases in animals," said Dr. Hermann Unger, project manager for the Joint FAO/IAEA Programme in Vienna. "To implement an effective containment strategy, we must have affordable, portable, quality assured and easy to use testing procedures. By enhancing our ability to obtain information about possible outbreaks, we hope to enable Member States to rapidly implement control measures. We appreciate QIAGEN's cooperation, technological expertise and logistical competence in developing this high-performance platform to our specific needs as part of the effort to contain these devastating animal diseases." The spread of so-called transboundary animal diseases causes widespread hardship, especially in the developing world. Avian Flu (H5N1) outbreaks, for example, have led to threats of human infection in addition to the destruction of millions of domestic fowl in Asia, Africa and Europe. In 1995, an epidemic of CBPP in Botswana caused economic damage of $500 million. Around the world, more than one billion sheep and goats, or approximately 60% of all small ruminants, are currently at risk of PPR. The FAO/IAEA initiative aims to use advanced QIAGEN technologies to help rapidly quell these types of outbreaks. QIAGEN's innovative ESE-Quant Tube Scanner can be deployed in almost any setting. Activated with a single button, the easy-to-use test is based on isothermal nucleic acid amplification, which allows DNA or RNA from viruses in sample materials to be multiplied and visualized without need for laboratory conditions. The instrument continuously takes extremely sensitive measurements, while also providing quality control of the results. The portable devices can process up to eight samples simultaneously within approximately 30 minutes, and results can be forwarded directly to a personal computer or notebook. QIAGEN N.V., a Netherlands holding company, is the leading global provider of sample and assay technologies. Sample technologies are used to isolate and process DNA, RNA and proteins from biological samples such as blood or tissue. Assay technologies are used to make such isolated bio-molecules visible. QIAGEN has developed and markets more than 500 sample and assay products as well as automated solutions for such consumables. The company provides its products to molecular diagnostics laboratories, academic researchers, pharmaceutical and biotechnology companies, and applied testing customers for purposes such as forensics, animal or food testing and pharmaceutical process control. QIAGEN's assay technologies include one of the broadest panels of molecular diagnostic tests available worldwide. This panel includes the digene HPV Test, which is regarded as a "gold standard" in testing for high-risk types of human papillomavirus (HPV), the primary cause of cervical cancer, as well as a broad suite of solutions for infectious disease testing and companion diagnostics. QIAGEN employs nearly 3,600 people in over 30 locations worldwide. Further information about QIAGEN can be found at http://www.qiagen.com/. The Joint FAO/IAEA Programme assists Member Countries of FAO and IAEA to use nuclear techniques and related biotechnologies for developing improved strategies for sustainable food security. Certain of the statements contained in this news release may be considered forward-looking statements within the meaning of Section 27A of the U.S. Securities Act of 1933, as amended, and Section 21E of the U.S. Securities Exchange Act of 1934, as amended. To the extent that any of the statements contained herein relating to QIAGEN's products, markets, strategy or operating results are forward-looking, such statements are based on current expectations that involve a number of uncertainties and risks. Such uncertainties and risks include, but are not limited to, risks associated with management of growth and international operations (including the effects of currency fluctuations and risks of dependency on logistics), variability of operating results, the commercial development of the applied testing markets, clinical research markets and proteomics markets, nucleic acid-based molecular diagnostics market, and genetic vaccination and gene therapy markets, competition, rapid or unexpected changes in technologies, fluctuations in demand for QIAGEN's products (including fluctuations due to the level and timing of customers' funding, budgets, and other factors), our ability to obtain regulatory approval of our infectious disease panels, difficulties in successfully adapting QIAGEN's products to integrated solutions and producing such products, the ability of QIAGEN to identify and develop new products and to differentiate its products from competitors' products, market acceptance of QIAGEN's new products and the integration of acquired technologies and businesses. For further information, refer to the discussions in reports that QIAGEN has filed with, or furnished to, the U.S. Securities and Exchange Commission (SEC).
QIAGEN Supplies Point-of-need Molecular Testing Devices For Animal Disease Surveillance in Emerging Countries
About QIAGEN
About Joint FAO / IAEA Programme
Related Documents
List of participating countries (PDF , 238.00 KB)
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