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罗氏收购英国核酸纯化技术公司Lumora

互联网2015年8月26日 15:35 点击:1771

瑞士罗氏Roche 

 

为了进一步完善高通量测序技术体系,罗氏公司(Roche)于8月24日宣布已与Lumora公司签订协议,收购Lumora用于测序样品准备的核酸纯化技术。

 

Lumora的核酸纯化技术,适用于多种样品类型,例如福尔马林固定石蜡包埋(FFPE)的肿瘤样本。核酸纯化技术能够在数分钟内自主分离FFPE组织样本的核酸,速度远超其他技术。该技术还可以应用于全血、排泄物质、唾液样本等等。这项技术仅限于科研。

 

在声明中,Lumora 首席执行官 Laurence Tisi 将核酸提取成为测序流程的“瓶颈”步骤。Lumora的热洗脱技术显著简化了提取的过程,使其自动化。

 

今年,罗氏一直紧抓“小收购”方针,为建立自己的测序技术体系,进行了一系列收购动作:上周,收购美国基因技术公司Kapa Biosystems;8月初,以4.25亿美元高价收购体外诊断公司GeneWeave;4月,收购 CAPP Medical,一家专注于利用NGS开发通过检测血液中循环肿瘤DNA(circulating tumor DNA,ctDNA)进行癌症筛查和监测的公司。

 

罗氏表示将把核酸纯化先进技术应用到测序工作中,对其集成测序体系、开拓NGS领域有着重要意义。

Roche Buys Lumora's Nucleic Acid Purification Technology

Roche is purchasing Lumora's products associated with its heat elution technology for nucleic acid purification. The technology can be used for multiple sample types, such as formalin-fixed paraffin-embedded tumor samples, and Roche said that it plans to integrate the technology into its sequencing workflow solution. 

The technology is for research use only. 

Lumora's technology enables automated nucleic acid isolation from FFPE in minutes, as opposed to hours with other technologies, Roche said. The technology can also be used with whole blood, fecal matter, sputum, and buccal swabs. 

In a statement, Lumora CEO Laurence Tisi called nucleic acid extraction an "important bottleneck in [the] sequencing workflow. Heat elution technology significantly simplifies extraction and is simple to automate. The acquisition of this technology may offer Roche a unique position in fully integrated sequencing devices." 

Financial and other terms of the deal were not disclosed. 

The deal is the latest in a recent string of transactions by Roche to build up its technology capabilities. Last week, it announced an agreement to buy molecular biology enzyme firm Kapa Biosystems. Earlier in the month, Roche also agreed to buy clinical diagnostics firm GeneWeave for as much as $425 million; and in the spring, it acquired CAPP Medical, which specializes in next-generation sequencing-based analysis of circulating tumor DNA for cancer screening and monitoring.

(来源: 互联网 )


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